Ashwagandha for Stress: What Science Actually Says

Ashwagandha for Stress: What Science Actually Says

Adaptogens are everywhere — but only a few have real clinical backing. We break down the trials.

Ashwagandha (Withania somnifera) is one of the most studied adaptogens. A 2019 double-blind trial (n=60) showed a 44% reduction in perceived stress and a 28% drop in morning cortisol after 8 weeks of 300mg KSM-66 extract.

It works by modulating the HPA axis — the body's stress-response system — rather than sedating it. Users report calmer mornings, steadier energy and better sleep within 2-4 weeks.

Dose and form matter: standardised root extract (KSM-66 or Sensoril) at 300-600mg/day is the clinically validated range. ENER uses KSM-66 at the trial dose.

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